- 名称:Seletalisib (UCB-5857)
- 简介:Seletalisib is a novel small-molecule inhibitor of PI3Kδ with an IC50 value of 12 nM and shows significant selectivity to PI3Kδ with respect to the other class I PI3K isoforms (between 24- and 303-fold).
- CASNO:1362850-20-1
- 分子式:C23H14ClF3N6O
- 分子量:482.85
- SMILES:FC(F)(F)[C@@H](C1=CC2=CC=CC(Cl)=C2N=C1C3=CC=C[N+]([O-])=C3)NC4=C5C(C=CC=N5)=NC=N4
- 保持条件:at -20°C 3 years Powder
- 同名:UCB-5857; UCB 5857; UCB5857; Seletalisib
- 纯度:>98%
- 应用:PI3K inhibitor
- 作用机制:Inhibitor