• 名称：PF-06409577
• 简介：PF-06409577 is orally bioavailable AMPK activator with EC50 of 7 nM for α1β1γ1 in the TR-FRET assay and it shows no detectable inhibition of hERG in a patch-clamp assay (100 μM) and was not an inhibitor (IC50 > 100 μM) of the microsomal activities of major human cytochrome P450 isoforms.
• CASNO：1467057-23-3
• 分子式：C19H16ClNO3
• 分子量：341.79
• SMILES：O=C(C1=CNC2=C1C=C(C3=CC=C(C4(O)CCC4)C=C3)C(Cl)=C2)O
• 保持条件：at -20°C 3 years Powder
• 同名：PF06409577, PF 06409577
• 纯度：>98%
• 应用：AMPK activator