- 名称:FM-381
- 简介:FM-381 is a JAK3 specific reversible covalent inhibitor with IC50 of 127 pM for JAK3 and demonstrates 400-, 2,700- and 3,600-fold selectivity over JAK1, JAK2, and TYK2, respectively.
- CASNO:N
- 分子式:C24H24N6O2
- 分子量:428.496
- SMILES:O=C(N(C)C)/C(C#N)=C/C(O1)=CC=C1C2=NC3=CN=C(NC=C4)C4=C3N2C5CCCCC5
- 保持条件:at -20°C 3 years Powder
- 同名:FM 381, FM381
- 纯度:>98%
- 应用:JAK3 inhibitor
- 作用机制:Inhibitor