- 名称:LY 3200882
- 简介:LY 3200882 is a potent, highly selective inhibitor of TGF-β receptor type 1 (TGFβRI). It potently inhibits TGFβ mediated SMAD phosphorylation in vitro in tumor and immune cells and in vivo in subcutaneous tumors in a dose dependent fashion.
- CASNO:1898283-02-7
- 分子式:C24H29N5O3
- 分子量:435.52
- SMILES:CC(O)(C)C1=NC=CC(NC2=NC=CC(OC3=CN(C4CC4)N=C3C5CCOCC5)=C2)=C1
- 保持条件:at -20°C 3 years Powder
- 同名:LY-3200882, LY3200882
- 纯度:>98%
- 应用:TGFβRI inhibitor
- 作用机制:Inhibitor