- 名称:Canagliflozin hemihydrate
- 简介:Canagliflozin hemihydrate is the hemihydrate form of canagliflozin, which is a SGLT2 inhibitor with IC50 of 2.2 nM for hSGLT2 in a cell-free assay, exhibits 413-fold selectivity over hSGLT1.
- CASNO:928672-86-0
- 分子式:C48H52F2O11S2
- 分子量:907.05
- SMILES:O[C@H]1C(O[C@@H]([C@H]([C@@H]1O)O)CO)C2=CC=C(C(CC3=CC=C(S3)C4=CC=C(C=C4)F)=C2)C.[H]O[H].O[C@H]5C(O[C@@H]([C@H]([C@@H]5O)O)CO)C6=CC=C(C(CC7=CC=C(S7)C8=CC=C(C=C8)F)=C6)C
- 保持条件:at -20°C 3 years Powder
- 同名:JNJ 28431754; JNJ-28431754; JNJ28431754; TA 7284; TA-7284; TA7284; JNJ-24831754-ZAE; JNJ-28431754-AAA
- 纯度:>98%
- 应用:SGLT2 inhibitor
- 作用机制:Inhibitor