• 名称：Derazantinib (ARQ-087)
• 简介：Derazantinib(ARQ-087) is an orally bioavailable inhibitor of the fibroblast growth factor receptor (FGFR) with IC50 values of 1.8 nM for FGFR2, and 4.5 nM for FGFR1 and 3, showing lower potency for FGFR4 (IC50=34 nM). It also inhibits RET, DDR2, PDGFRβ, VEGFR and KIT.
• CASNO：1234356-69-4
• 分子式：C29H29FN4O
• 分子量：468.57
• SMILES：COCCNCCC1=CC(NC2=NC=C3C[C@@H](C4=CC=CC=C4F)C5=CC=CC=C5C3=N2)=CC=C1
• 保持条件：at -20°C 3 years Powder
• 同名：ARQ087, ARQ 087
• 纯度：>98%
• 应用：FGFR inhibitor
• 作用机制：Inhibitor