• 名称：Lazertinib (YH25448,GNS-1480)
• 简介：Lazertinib (YH25448,GNS-1480) is a potent, highly mutant-selective and irreversible EGFR-TKI with IC50 values of 1.7 nM, 2 nM, 5 nM, 20.6 nM and 76 nM for Del19/T790M, L858R/T790M, Del19, L85R and Wild type EGFR respectively, showing much higher IC50 values aganist ErbB2 and ErbB4.
• CASNO：1903008-80-9
• 分子式：C30H34N8O3
• 分子量：554.66
• SMILES：C=CC(NC1=CC(NC2=NC=CC(N3N=C(C4=CC=CC=C4)C(CN(C)C)=C3)=N2)=C(OC)C=C1N5CCOCC5)=O
• 保持条件：at -20°C 3 years Powder
• 同名：YH 25448, YH-25448, GNS1480, GNS 1480
• 纯度：>98%
• 应用：EGFR inhibitor
• 作用机制：Inhibitor