• 名称：A-485
• 简介：A-485 is a potent and selective HAT inhibitor of p300/CBP in vitro with an IC50 of 10 nM in a p300 TR-FRET assay and 3 nM in a CBP TR-FRET assay with selectivity > 1000-fold over closely related HATs.
• CASNO：1889279-16-6
• 分子式：C25H24F4N4O5
• 分子量：536.48
• SMILES：O=C(N1CC(N([C@H](C(F)(F)F)C)CC2=CC=C(F)C=C2)=O)[C@@]3(OC1=O)CCC4=CC(NC(NC)=O)=CC=C43
• 保持条件：at -20°C 3 years Powder
• 同名：A 485, A485
• 纯度：>98%
• 应用：p300/CBP inhibitor
• 作用机制：Inhibitor