- 名称:CBL-0137
- 简介:CBL0137(CBL-0137) activates p53 and inhibits NF-kB with EC50s of 0.37 μM and 0.47 μM in the cell-based p53 and NF-kB reporter assays, respectively. It also inhibits histone chaperone FACT (facilitates chromatin transcription complex).
- CASNO:1197397-89-9
- 分子式:C21H24N2O2.HCl
- 分子量:372.89
- SMILES:CC(/N=C/CN1C2=C(C3=C1C=CC(C(C)=O)=C3)C=C(C(C)=O)C=C2)C.[H]Cl
- 保持条件:at -20°C 3 years Powder
- 同名:CBL0137, CBL 0137, Curaxin 137, Curaxin137, Curaxin-137, CBLC137, CBLC 137, CBLC-137
- 纯度:>98%
- 应用:p53 activator / NF-κB inhibitor
- 作用机制:Inhibitor