• 名称：MK-8353 (SCH900353)
• 简介：MK-8353 (SCH900353) is an orally bioavailable, selective, and potent ERK inhibitor that inhibits activated ERK1 and ERK2 in vitro, with IC50 values of 23.0 nM and 8.8 nM, respectively (IMAP kinase assay), and nonactivated ERK2, with an IC50 of 0.5 nM (MEK1-ERK2-coupled assay).
• CASNO：1184173-73-6
• 分子式：C37H41N9O3S
• 分子量：691.84
• SMILES：O=C(CN1CC[C@@](SC)(C(NC2=CC=C(NN=C3C4=CC=C(OC(C)C)N=C4)C3=C2)=O)C1)N5CCC(C6=CC=C(C7=NN(C)C=N7)C=C6)=CC5
• 保持条件：at -20°C 3 years Powder
• 同名：MK8353, MK 8353, SCH 900353, SCH-900353
• 纯度：>98%
• 应用：ERK inhibitor
• 作用机制：Inhibitor