- 名称:PLX8394
- 简介:PLX8394 is a next-generation, orally available, small-molecule BRAF inhibitor with IC50 values of 3.8 nM, 14 nM and 23 nM for BRAF(V600E), WT BRAF and CRAF respectively. It has potential antineoplastic activity.
- CASNO:1393466-87-9
- 分子式:C25H21F3N6O3S
- 分子量:542.53
- SMILES:O=S(N1C[C@H](F)CC1)(NC2=CC=C(F)C(C(C3=CNC4=NC=C(C5=CN=C(C6CC6)N=C5)C=C43)=O)=C2F)=O
- 保持条件:at -20°C 3 years Powder
- 同名:PLX 8394, PLX-8394
- 纯度:>98%
- 应用:BRAF inhibitor
- 作用机制:Inhibitor