- 名称:LYN-1604
- 简介:LYN-1604 is a potential ULK1 agonist with IC50 of 1.66 μM against MDA-MB-231 cells and it binds to wild-type ULK1 with a binding affinity in the nanomole range (Kd=291.4 nM). The ULK1 (Y89A) mutant protein caused a sharp decrease in binding affinity with lower response and Kd than wild-type ULK1, ULK1 (K50A) and ULK1 (L53A) mutants.
- CASNO:2088939-99-3
- 分子式:C33H45Cl4N3O2
- 分子量:657.54
- SMILES:CC(C)CN(CC(N1CCN(CC(C2=CC=C(Cl)C=C2Cl)OCC3=CC=C4C=CC=CC4=C3)CC1)=O)CC(C)C
- 保持条件:at -20°C 3 years Powder
- 同名:LYN 1604, LYN1604
- 纯度:>98%
- 应用:ULK1 agonist
- 作用机制:Agonist