• 名称：Avadomide (CC-122)
• 简介：Avadomide(CC-122), a new chemical entity termed pleiotropic pathway modifier, is a novel agent for Diffuse large B-cell lymphoma(DLBCL) with antitumor and immunomodulatory activity. Its molecular target is the protein cereblon (CRBN), a substrate receptor of the cullin ring E3 ubiquitin ligase complex CRL4CRBN.
• CASNO：1015474-32-4
• 分子式：C14H14N4O3
• 分子量：286.29
• SMILES：O=C(C(N1C(C)=NC2=C(C(N)=CC=C2)C1=O)CC3)NC3=O
• 保持条件：at -20°C 3 years Powder
• 同名：CC122, CC 122
• 纯度：>98%
• 应用：E3 Ligase inhibitor
• 作用机制：Inhibitor