- 商品货号:A16925
- 名称:Esaxerenone
- 简介:Esaxerenone, also known as CS-3150, XL-550, is a nonsteroidal antimineralocorticoid that acts as a highly selective silent antagonist of the mineralocorticoid receptor (MR), the receptor for aldosterone, with greater than 1,000-fold selectivity for this receptor over other steroid hormone receptors, and 4-fold and 76-fold higher affinity for the MR relative to the existing antimineralocorticoids spironolactone and eplerenone.
- CASNO:1632006-28-0
- 分子式:C22H21F3N2O4S
- 分子量:466.47
- SMILES:CS(C1=CC=C(NC(C2=CN(CCO)C(C3=CC=CC=C3C(F)(F)F)=C2C)=O)C=C1)(=O)=O
- 保持条件:at -20°C 3 years Powder
- 同名:CS-3150, CS 3150, CS3150, XL-550, XL550, L 550
- 纯度:>98%
- 应用:Aldosterone Receptor Antagonist
- 作用机制:Antagonist