- 名称:THZ531
- 简介:THZ531 is a covalent CDK12 and CDK13 covalent inhibitor. THZ531 irreversibly targets a cysteine located outside the kinase domain. THZ531 causes a loss of gene expression with concurrent loss of elongating and hyperphosphorylated RNA polymerase II.
- CASNO:1702809-17-3
- 分子式:C30H32ClN7O2
- 分子量:558.08
- 保持条件:at -20°C 3 years Powder
- 同名:THZ-531, THZ 531
- 纯度:>98%
- 应用:CDK12 and CDK13 covalent inhibitor