- 名称:Timegadine
- 简介:Timegadine, a new antiinflammatory agent, is found to be a potent, competitive inhibitor of cyclo-oxygenase (COX) and lipo-oxygenase, with IC50s ranging from 5 nM (washed rabbit platelets) to 20 μM (rat brain) for COX and 100 μM for lipo-oxygenase both in the cytosol fraction of horse platelet homogenates, and in washed rabbit platelets.
- CASNO:71079-19-1
- 分子式:C20H23N5S
- 分子量:365.5
- SMILES:CC1=NC2=CC=CC=C2C(/N=C(NC3CCCCC3)/NC4=NC=CS4)=C1
- 保持条件:at -20°C 3 years Powder
- 同名:SR 1368, SR-1368, SR1368
- 纯度:>98%
- 应用:COX and lipo-oxygenase inhibitor
- 作用机制:Inhibitor