IGROV1细胞（人卵巢癌细胞/卵巢子宫内膜样腺癌）

商品货号：CL0696

￥1500元

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商品描述 STR鉴定

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细胞信息

发货规格 1×10⁶
别名 Igrov-1; IGROV 1; IGR-OV1; IGROV1; Igrov1; IGR.OV1; IGROV; OV1/P; OV1/p; OV1-P
形态上皮细胞样
生长特性贴壁
培养条件 RPMI-1640+10%FBS+1%P/S
冻存条件 90%FBS+10%DMSO
传代方式胰酶消化
倍增时间 30h
传代比例 1:2~1:4
换液频率每周2~3次
生物安全等级 1

细胞背景

种属人源
组织来源卵巢
肿瘤类型卵巢癌
供体信息 47岁女性
背景描述 IGROV-1 细胞是从一名 47 岁女性患者的 III 期卵巢实体原发性肿瘤中建立的，IGROV-1 细胞缺乏激素受体，对几种常见化疗药物表现出低至中度敏感性，同时对顺铂仍敏感

遗传背景

蛋白表达 expression of vitronectin and αvβ3 integrin，and express the cancer-associated target MDM2
致瘤性 IGROV-1 cells appear in culture as confluent monolayers and are highly tumorigenic in vivo， forming solid tumors within 15 days in nude mice
核型 IGROV-1 cells harbor a paracentric inversion of chromosome 3 and a translocation between chromosomes 2 and 5

STR鉴定

STR位点信息

STR鉴定图

Amelogenin X
CSF1PO 11,12,13,14,15,16 (Millipore=SCC203) 11,13 (PubMed=19372543; PubMed=30485824) 11,13,14,15 (Cosmic-CLP=905968) 11,13,15 (PubMed=25877200) 11,16 (PubMed=25230021)
D2S1338 17,25
D3S1358 13,14,15 (Millipore=SCC203; PubMed=25230021; PubMed=25877200) 13,15 (PubMed=19372543)
D5S818 11,12,13 (Millipore=SCC203) 12 (PubMed=25877200; PubMed=30485824) 12,13 (Cosmic-CLP=905968; PubMed=19372543; PubMed=25230021)
D7S820 9.1,10.1,11.1 (PubMed=25230021) 9.3,10.1 (PubMed=30485824) 10 (PubMed=25877200) 10,10.1,10.3,11.1 (Millipore=SCC203) 11 (Cosmic-CLP=905968)
D8S1179 13,14,15,16,17 (Millipore=SCC203) 14,16 (PubMed=25230021; PubMed=25877200)
D13S317 8,10
D16S539 10,11,12,13 (Millipore=SCC203) 11,12 (Cosmic-CLP=905968; PubMed=19372543; PubMed=25877200) 11,13 (PubMed=30485824) 12 (PubMed=25230021)
D18S51 14,15,16 (Millipore=SCC203) 14,16,17 (PubMed=25230021) 15,16 (PubMed=25877200)
D19S433 13,14
D21S11 26,29.2,30.2 (PubMed=25230021) 26,30.2 (PubMed=25877200; PubMed=30485824) 26,30.2,31.2 (Millipore=SCC203)
FGA 20,21,26 (PubMed=25230021) 21,25,26 (Millipore=SCC203) 21,26 (PubMed=25877200)
Penta D 8,10
Penta E 13,17
TH01 7,9.3
TPOX 8,11 (Millipore=SCC203; PubMed=19372543; PubMed=25230021; PubMed=25877200; PubMed=30485824) 8,11,12 (Cosmic-CLP=905968)
vWA 16,17,20,21,22 (Millipore=SCC203) 16,17,20,22 (PubMed=25230021) 17,21 (Cosmic-CLP=905968; PubMed=19372543; PubMed=30485824) 17,21,22 (PubMed=25877200)

细胞信息
发货规格	1×10⁶
别名	Igrov-1; IGROV 1; IGR-OV1; IGROV1; Igrov1; IGR.OV1; IGROV; OV1/P; OV1/p; OV1-P
形态	上皮细胞样
生长特性	贴壁
培养条件	RPMI-1640+10%FBS+1%P/S
冻存条件	90%FBS+10%DMSO
传代方式	胰酶消化
倍增时间	30h
传代比例	1:2~1:4
换液频率	每周2~3次
生物安全等级	1
细胞背景
种属	人源
组织来源	卵巢
肿瘤类型	卵巢癌
供体信息	47岁女性
背景描述	IGROV-1 细胞是从一名 47 岁女性患者的 III 期卵巢实体原发性肿瘤中建立的，IGROV-1 细胞缺乏激素受体，对几种常见化疗药物表现出低至中度敏感性，同时对顺铂仍敏感
遗传背景
蛋白表达	expression of vitronectin and αvβ3 integrin，and express the cancer-associated target MDM2
致瘤性	IGROV-1 cells appear in culture as confluent monolayers and are highly tumorigenic in vivo， forming solid tumors within 15 days in nude mice
核型	IGROV-1 cells harbor a paracentric inversion of chromosome 3 and a translocation between chromosomes 2 and 5

Amelogenin	X
CSF1PO	11,12,13,14,15,16 (Millipore=SCC203) 11,13 (PubMed=19372543; PubMed=30485824) 11,13,14,15 (Cosmic-CLP=905968) 11,13,15 (PubMed=25877200) 11,16 (PubMed=25230021)
D2S1338	17,25
D3S1358	13,14,15 (Millipore=SCC203; PubMed=25230021; PubMed=25877200) 13,15 (PubMed=19372543)
D5S818	11,12,13 (Millipore=SCC203) 12 (PubMed=25877200; PubMed=30485824) 12,13 (Cosmic-CLP=905968; PubMed=19372543; PubMed=25230021)
D7S820	9.1,10.1,11.1 (PubMed=25230021) 9.3,10.1 (PubMed=30485824) 10 (PubMed=25877200) 10,10.1,10.3,11.1 (Millipore=SCC203) 11 (Cosmic-CLP=905968)
D8S1179	13,14,15,16,17 (Millipore=SCC203) 14,16 (PubMed=25230021; PubMed=25877200)
D13S317	8,10
D16S539	10,11,12,13 (Millipore=SCC203) 11,12 (Cosmic-CLP=905968; PubMed=19372543; PubMed=25877200) 11,13 (PubMed=30485824) 12 (PubMed=25230021)
D18S51	14,15,16 (Millipore=SCC203) 14,16,17 (PubMed=25230021) 15,16 (PubMed=25877200)
D19S433	13,14
D21S11	26,29.2,30.2 (PubMed=25230021) 26,30.2 (PubMed=25877200; PubMed=30485824) 26,30.2,31.2 (Millipore=SCC203)
FGA	20,21,26 (PubMed=25230021) 21,25,26 (Millipore=SCC203) 21,26 (PubMed=25877200)
Penta D	8,10
Penta E	13,17
TH01	7,9.3
TPOX	8,11 (Millipore=SCC203; PubMed=19372543; PubMed=25230021; PubMed=25877200; PubMed=30485824) 8,11,12 (Cosmic-CLP=905968)
vWA	16,17,20,21,22 (Millipore=SCC203) 16,17,20,22 (PubMed=25230021) 17,21 (Cosmic-CLP=905968; PubMed=19372543; PubMed=30485824) 17,21,22 (PubMed=25877200)

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