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人IL6ST(NM_002184)ORF克隆
人IL6ST(NM_002184)ORF克隆
  • 商品货号:FO124299
  • 已售 3 件 | 评价 0 人次 | 关注度 281
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    • accession:NM_002184
    • 基因别名:IL6ST
    • 基因描述:Homo sapiens interleukin 6 signal transducer (gp130, oncostatin M receptor) (IL6ST), transcript variant 1, mRNA.
    • 载体: 现货载体
    • CDS区长度:2757
    • 翻译后氨基酸长度:918
    • TranscriptVariant:This variant (1) encodes represents the longest transcript and encodes the longest isoform (1).
    • 基因简介:The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described. A related pseudogene has been identified on chromosome 17. [provided by RefSeq, Jul 2010]
    • 载体信息:自有图片地址
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列