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人CENPJ(NM_018451)ORF克隆
人CENPJ(NM_018451)ORF克隆
  • 商品货号:FO124436
  • 已售 3 件 | 评价 0 人次 | 关注度 401
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    • accession:NM_018451
    • 基因别名:CENPJ
    • 基因描述:Homo sapiens centromere protein J (CENPJ), transcript variant 1, mRNA.
    • 载体: 现货载体
    • CDS区长度:4017
    • 翻译后氨基酸长度:1338
    • TranscriptVariant:This variant (1) represents the protein coding transcript.
    • 基因简介:This gene encodes a protein that belongs to the centromere protein family. During cell division, this protein plays a structural role in the maintenance of centrosome integrity and normal spindle morphology, and it is involved in microtubule disassembly at the centrosome. This protein can function as a transcriptional coactivator in the Stat5 signaling pathway, and also as a coactivator of NF-kappaB-mediated transcription, likely via its interaction with the coactivator p300/CREB-binding protein. Mutations in this gene are associated with primary autosomal recessive microcephaly, a disorder characterized by severely reduced brain size and mental retardation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2012]
    • 载体信息:自有图片地址
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列