- accession:NM_005135
- 基因别名:SLC12A6
- 基因描述:Homo sapiens solute carrier family 12 (potassium/chloride transporter), member 6 (SLC12A6), transcript variant 2, mRNA.
- 载体: 现货载体
- CDS区长度:3300
- 翻译后氨基酸长度:1099
- TranscriptVariant:This variant (2) uses an alternate exon for the 5' UTR and 5' coding region, compared to variant 1. The encoded protein (isoform b) is shorter and has a distinct N-terminus, compared to isoform a.
- 基因简介:This gene is a member of the K-Cl cotransporter (KCC) family. K-Cl cotransporters are integral membrane proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The proteins encoded by this gene are activated by cell swelling induced by hypotonic conditions. Alternate splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are associated with agenesis of the corpus callosum with peripheral neuropathy. [provided by RefSeq, Jul 2008]
- 载体信息:自有图片地址
- 规格:10ul 质粒
CDS区参考序列: 点击查看序列翻译后氨基酸参数序列: 点击查看序列