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人TLR5(NM_003268)ORF克隆
人TLR5(NM_003268)ORF克隆
  • 商品货号:FO124720
  • 已售 3 件 | 评价 0 人次 | 关注度 416
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    • accession:NM_003268
    • 基因别名:TLR5
    • 基因描述:Homo sapiens toll-like receptor 5 (TLR5), mRNA.
    • 载体: 现货载体
    • CDS区长度:2577
    • 翻译后氨基酸长度:858
    • 基因简介:This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.[provided by RefSeq, Dec 2009]
    • 载体信息:自有图片地址
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列