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人RASGRP1(NM_005739)ORF克隆
人RASGRP1(NM_005739)ORF克隆
  • 商品货号:FO124880
  • 已售 3 件 | 评价 0 人次 | 关注度 265
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    • accession:NM_005739
    • 基因别名:RASGRP1
    • 基因描述:Homo sapiens RAS guanyl releasing protein 1 (calcium and DAG-regulated) (RASGRP1), transcript variant 1, mRNA.
    • 载体: 现货载体
    • CDS区长度:2394
    • 翻译后氨基酸长度:797
    • TranscriptVariant:This variant (1) represents the longer transcript, and encodes the longer isoform (a).
    • 基因简介:This gene is a member of a family of genes characterized by the presence of a Ras superfamily guanine nucleotide exchange factor (GEF) domain. It functions as a diacylglycerol (DAG)-regulated nucleotide exchange factor specifically activating Ras through the exchange of bound GDP for GTP. It activates the Erk/MAP kinase cascade and regulates T-cells and B-cells development, homeostasis and differentiation. Alternatively spliced transcript variants encoding different isoforms have been identified. Altered expression of the different isoforms of this protein may be a cause of susceptibility to systemic lupus erythematosus (SLE). [provided by RefSeq, Jul 2008]
    • 载体信息:自有图片地址
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列