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人PRMT6(NM_018137)ORF克隆
人PRMT6(NM_018137)ORF克隆
会员等级价V
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  • 商品货号:F125219
  • accession:NM_018137
  • 基因别名:PRMT6
  • 基因描述:Homo sapiens protein arginine methyltransferase 6 (PRMT6), mRNA.
  • 载体: 现货载体
  • CDS区长度:1128
  • 翻译后氨基酸长度:375
  • 基因简介:The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity. [provided by RefSeq, Sep 2011]
  • 载体信息:自有图片地址
  • 规格:10ul 质粒
CDS区参考序列: 点击查看序列
翻译后氨基酸参数序列: 点击查看序列