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人DAZL(NM_001351)ORF克隆
人DAZL(NM_001351)ORF克隆
会员等级价V
已售 5 件 | 评价 0 人次 | 关注度 375
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  • 商品货号:F132701
  • accession:NM_001351
  • 基因别名:DAZL
  • 基因描述:Homo sapiens deleted in azoospermia-like (DAZL), transcript variant 2, mRNA.
  • 载体: 现货载体
  • CDS区长度:888
  • 翻译后氨基酸长度:295
  • TranscriptVariant:This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (2) has a shorter and distinct N-terminus compared to isoform 2.
  • 基因简介:The DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. The protein encoded by this gene is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of this autosomal gene during primate evolution gave rise to the DAZ gene cluster on the Y chromosome. Mutations in this gene have been linked to severe spermatogenic failure and infertility in males. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
  • 载体信息:自有图片地址
  • 规格:10ul 质粒
CDS区参考序列: 点击查看序列
翻译后氨基酸参数序列: 点击查看序列