• 商品货号：F138393

• accession：NM_145309
• 基因别名：LRTOMT
• 基因描述：Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant 1, mRNA.
• 载体：现货载体
• CDS区长度：579
• 翻译后氨基酸长度：192
• TranscriptVariant：This variant (1, also known as A) represents the short transcript form. It encodes the longest isoform (LRTOMT1a) of the leucine-rich repeat (LRR)-containing protein. This protein is supported by Western blot as reported in PMID:18953341.
• 基因简介：This gene includes two transcript forms. The short form has one open reading frame (ORF), which encodes the leucine-rich repeats (LRR)-containing protein of unknown function. This protein is called LRTOMT1 or LRRC51. The long form has two alternative ORFs; the upstream ORF has the same translation start codon as used in the short form and the resulting transcript is a candidate for nonsense-mediated decay, and the downstream ORF encodes a different protein, which is a transmembrane catechol-O-methyltransferase and is called LRTOMT2, TOMT or COMT2. The COMT2 is essential for auditory and vestibular function. Defects in the COMT2 can cause nonsyndromic deafness. Alternatively spliced transcript variants from each transcript form have been found for this gene. [provided by RefSeq, Sep 2012]
• 载体信息：自有图片地址
• 规格：10ul 质粒

CDS区参考序列： 点击查看序列

ATGAACAAACGGGACTATATGAACACTTCGGTACAGGAGCCCCCTCTTGACTACTCCTTCAGAAGCATCCACGTCATTCAAGATCTGGTAAATGAGGAGCCAAGGACAGGACTACGACCACTGAAGCGTTCAAAGTCGGGGAAATCACTGACCCAGTCCCTGTGGCTGAATAACAATGTTCTCAATGATCTGAGAGACTTCAACCAGGTGGCTTCACAGCTGTTGGAGCACCCAGAGAACCTGGCCTGGATCGACCTGTCCTTTAATGACCTGACTTCCATTGACCCTGTCCTAACAACTTTCTTCAACCTGAGTGTCCTCTATCTTCACGGCAACAGCATCCAGCGCCTGGGGGAGGTGAATAAGCTGGCTGTCCTTCCTCGGCTCCGTAGCCTGACACTCCATGGGAACCCCATGGAGGAAGAGAAAGGGTATAGGCAATATGTGCTGTGCACCCTGTCCCGTATCACCACGTTCGACTTCAGTGGGGTCACCAAAGCAGACCGCACCACAGCTGAAGTCTGGAAACGCATGAACATCAAGCCCAAGAAGGCCTGGACCAAGCAGAATACACTTTGA

翻译后氨基酸参数序列： 点击查看序列

ATGAACAAACGGGACTATATGAACACTTCGGTACAGGAGCCCCCTCTTGACTACTCCTTCAGAAGCATCCACGTCATTCAAGATCTGGTAAATGAGGAGCCAAGGACAGGACTACGACCACTGAAGCGTTCAAAGTCGGGGAAATCACTGACCCAGTCCCTGTGGCTGAATAACAATGTTCTCAATGATCTGAGAGACTTCAACCAGGTGGCTTCACAGCTGTTGGAGCACCCAGAGAACCTGGCCTGGATCGACCTGTCCTTTAATGACCTGACTTCCATTGACCCTGTCCTAACAACTTTCTTCAACCTGAGTGTCCTCTATCTTCACGGCAACAGCATCCAGCGCCTGGGGGAGGTGAATAAGCTGGCTGTCCTTCCTCGGCTCCGTAGCCTGACACTCCATGGGAACCCCATGGAGGAAGAGAAAGGGTATAGGCAATATGTGCTGTGCACCCTGTCCCGTATCACCACGTTCGACTTCAGTGGGGTCACCAAAGCAGACCGCACCACAGCTGAAGTCTGGAAACGCATGAACATCAAGCCCAAGAAGGCCTGGACCAAGCAGAATACACTTTGA