- 商品货号:F138956
- accession:NM_004463
- 基因别名:FGD1
- 基因描述:Homo sapiens FYVE, RhoGEF and PH domain containing 1 (FGD1), mRNA.
- 载体: 现货载体
- CDS区长度:2886
- 翻译后氨基酸长度:961
- 基因简介:This gene encodes a protein that contains Dbl (DH) and pleckstrin (PH) homology domains and is similar to the Rho family of small GTP-binding proteins. The encoded protein specifically binds to the Rho family GTPase Cdc42Hs and can stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. Defects in this gene are the cause of faciogenital dysplasia and X-linked mental retardation, syndromatic 16.[provided by RefSeq, Mar 2011]
- 载体信息:自有图片地址
- 规格:10ul 质粒
CDS区参考序列: 点击查看序列翻译后氨基酸参数序列: 点击查看序列