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人TLR9(NM_017442)ORF克隆
人TLR9(NM_017442)ORF克隆
¥2800元
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  • 商品货号:F154593
  • accession:NM_017442
  • 基因别名:TLR9
  • 基因描述:Homo sapiens toll-like receptor 9 (TLR9), mRNA.
  • 载体:现货载体
  • CDS区长度:3099
  • 翻译后氨基酸长度:1032
  • 基因简介:The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response. [provided by RefSeq, Jul 2008]
  • 载体信息:自有图片地址
  • 规格:10ul 质粒
CDS区参考序列: 点击查看序列
翻译后氨基酸参数序列: 点击查看序列