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人RFXAP(NM_000538)ORF克隆
人RFXAP(NM_000538)ORF克隆
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  • 商品货号:F157102
  • accession:NM_000538
  • 基因别名:RFXAP
  • 基因描述:Homo sapiens regulatory factor X-associated protein (RFXAP), mRNA.
  • 载体:现货载体
  • CDS区长度:819
  • 翻译后氨基酸长度:272
  • 基因简介:Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated ankyrin-containing protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group D. Transcript variants utilizing different polyA signals have been found for this gene. [provided by RefSeq, Jul 2008]
  • 载体信息:自有图片地址
  • 规格:10ul 质粒
CDS区参考序列: 点击查看序列
翻译后氨基酸参数序列: 点击查看序列