- 商品货号:F162039
- accession:NM_003317
- 基因别名:NKX2-1
- 基因描述:Homo sapiens NK2 homeobox 1 (NKX2-1), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:1116
- 翻译后氨基酸长度:371
- TranscriptVariant:This variant (2) differs in the 5' UTR and coding region compared to variant 1. The resulting protein (isoform 2) is shorter and has a distinct N-terminus compared to isoform 1.
- 基因简介:This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TFF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription. [provided by RefSeq, Apr 2011]
- 载体信息:自有图片地址
- 规格:10ul 质粒
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