- 商品货号:F163273
- accession:NM_003339
- 基因别名:UBE2D2
- 基因描述:Homo sapiens ubiquitin-conjugating enzyme E2D 2 (UBE2D2), transcript variant 1, mRNA.
- 载体:现货载体
- CDS区长度:444
- 翻译后氨基酸长度:147
- TranscriptVariant:This variant (1) encodes the longer isoform (1).
- 基因简介:Regulated degradation of misfolded, damaged or short-lived proteins in eukaryotes occurs via the ubiquitin (Ub)-proteasome system (UPS). An integral part of the UPS system is the ubiquitination of target proteins and covalent linkage of Ub-containing proteins to form polymeric chains, marking them as targets for 26S proteasome-mediated degradation. Ubiquitination of proteins is mediated by a cascade of enzymes which includes E1 (ubiquitin activating), E2 (ubiquitin conjugating), and E3 (ubiquitin ligases) enzymes. This gene encodes a member of the E2 enzyme family. Substrates of this enzyme include the tumor suppressor protein p53 and peroxisomal biogenesis factor 5 (PEX5). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013]
- 载体信息:自有图片地址
- 规格:10ul 质粒
CDS区参考序列: 点击查看序列翻译后氨基酸参数序列: 点击查看序列