服务热线：
- 商品货号：G167275
- accession：NM_004739
- 基因别名：PID; MTA1L1
- 基因描述：Homo sapiens metastasis associated 1 family, member 2 (MTA2), mRNA.
- 载体：现货载体
- CDS区长度：2007
- 翻译后氨基酸长度：668
- 基因简介：This gene encodes a protein that has been identified as a component of NuRD, a nucleosome remodeling deacetylase complex identified in the nucleus of human cells. It shows a very broad expression pattern and is strongly expressed in many tissues. It may represent one member of a small gene family that encode different but related proteins involved either directly or indirectly in transcriptional regulation. Their indirect effects on transcriptional regulation may include chromatin remodeling. It is closely related to another member of this family, a protein that has been correlated with the metastatic potential of certain carcinomas. These two proteins are so closely related that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. One of the proteins known to be a target protein for this gene product is p53. Deacetylation of p53 is correlated with a loss of growth inhibition in transformed cells supporting a connection between these gene family members and metastasis. [provided by RefSeq, May 2011]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
服务时间：24小时在线客服
客服热线：400-000-7085
丰晖生物
中国优质生物资源平台
在线客服