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- 商品货号：G100692
- accession：NM_207032
- 基因别名：EDN3
- 基因描述：Homo sapiens endothelin 3 (EDN3), transcript variant 2, mRNA.
- 载体：现货载体
- CDS区长度：660
- 翻译后氨基酸长度：219
- TranscriptVariant：This variant (2) uses an alternative splice site in the coding region and lacks a segment in the 3' UTR compared to variant 1. The resulting isoform (2) has a distinct and shorter C-terminus, as compared to isoform 1.
- 基因简介：The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Four alternatively spliced transcript variants encoding three distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
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