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- 商品货号：G100763
- accession：NM_001012965
- 基因别名：KLK6
- 基因描述：Homo sapiens kallikrein-related peptidase 6 (KLK6), transcript variant C, mRNA.
- 载体：现货载体
- CDS区长度：414
- 翻译后氨基酸长度：137
- TranscriptVariant：This variant (C), also called splice variant 2, differs in the 5' UTR and has multiple coding region differences, compared to variant A. These differences result in predicted translation initiation at a downstream ATG. The resulting isoform (B) has a shorter N-terminus when it is compared to isoform A. This transcript is supported by multiple ESTs, but the predicted ORF has not yet been experimentally confirmed.
- 基因简介：Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
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