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- 商品货号：G100870
- accession：NM_013324
- 基因别名：CISH
- 基因描述：Homo sapiens cytokine inducible SH2-containing protein (CISH), transcript variant 1, mRNA.
- 载体：现货载体
- CDS区长度：828
- 翻译后氨基酸长度：275
- TranscriptVariant：This variant (1) represents a longer transcript, and encodes an isoform (1) with a distinct N-terminus.
- 基因简介：The protein encoded by this gene contains a SH2 domain and a SOCS box domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by IL2, IL3, GM-CSF and EPO in hematopoietic cells. Proteasome-mediated degradation of this protein has been shown to be involved in the inactivation of the erythropoietin receptor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
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