- 商品货号:G102334
- accession:NM_001024628
- 基因别名:NRP1
- 基因描述:Homo sapiens neuropilin 1 (NRP1), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:1935
- 翻译后氨基酸长度:644
- TranscriptVariant:This variant (2) uses a different splice site in the 3' end and contains a different segment for the 3' end of the coding region and the 3' UTR, compared to variant 1. The resulting protein (isoform b) has a shorter C-terminus when compared to isoform a. This variant has also been named S12NRP1 in PubMed ID: 11112349.
- 基因简介:This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Oct 2011]
- 规格:10ul 质粒
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