- 商品货号:G102339
- accession:NM_001134
- 基因别名:AFP
- 基因描述:Homo sapiens alpha-fetoprotein (AFP), mRNA.
- 载体:pcDNA3.1-3xFlag-C
- CDS区长度:1830
- 翻译后氨基酸长度:609
- 基因简介:This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [provided by RefSeq, Jul 2008]
- 规格:10ul 质粒
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