- 商品货号:F102523
- accession:NM_016237
- 基因别名:ANAPC5
- 基因描述:Homo sapiens anaphase promoting complex subunit 5 (ANAPC5), transcript variant 1, mRNA.
- 载体: 现货载体
- CDS区长度:2268
- 翻译后氨基酸长度:755
- TranscriptVariant:This variant (1) represents the longer transcript and encodes the longer isoform (a).
- 基因简介:This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a. [provided by RefSeq, Nov 2008]
- 载体信息:自有图片地址
- 规格:10ul 质粒
CDS区参考序列: 点击查看序列翻译后氨基酸参数序列: 点击查看序列