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- 商品货号：G103949
- accession：NM_002555
- 基因别名：SLC22A18
- 基因描述：Homo sapiens solute carrier family 22, member 18 (SLC22A18), transcript variant 1, mRNA.
- 载体：现货载体
- CDS区长度：1275
- 翻译后氨基酸长度：424
- TranscriptVariant：This variant (1) represents the shorter transcript. Both variants 1 and 2 encode the same isoform.
- 基因简介：This gene is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene is imprinted, with preferential expression from the maternal allele. Mutations in this gene have been found in Wilms' tumor and lung cancer. This protein may act as a transporter of organic cations, and have a role in the transport of chloroquine and quinidine-related compounds in kidney. Two alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Oct 2010]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
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