- 商品货号:G105254
- accession:NM_177969
- 基因别名:PPM1B
- 基因描述:Homo sapiens protein phosphatase, Mg2+/Mn2+ dependent, 1B (PPM1B), transcript variant 3, mRNA.
- 载体:现货载体
- CDS区长度:579
- 翻译后氨基酸长度:192
- TranscriptVariant:This variant (3) lacks an internal segment, which includes a part of the coding region, as compared to variant 1. The translation begins at a downstream start codon, resulting in an isoform (3) that has a shorter N-terminus, as compared to isoform 1.
- 基因简介:The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences. [provided by RefSeq, Jul 2008]
- 规格:10ul 质粒
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