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- 商品货号：G108006
- accession：NM_001791
- 基因别名：CDC42
- 基因描述：Homo sapiens cell division cycle 42 (CDC42), transcript variant 1, mRNA.
- 载体：现货载体
- CDS区长度：576
- 翻译后氨基酸长度：191
- TranscriptVariant：This variant (1) encodes isoform 1 which has the same aa length but different C-terminus from isoform 2.
- 基因简介：The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20. [provided by RefSeq, Apr 2013]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
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