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人 CYBB (NM_000397) cDNA克隆
人 CYBB (NM_000397) cDNA克隆
¥1200元
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  • 商品货号:G112322
  • accession:NM_000397
  • 基因别名:CYBB
  • 基因描述:Homo sapiens cytochrome b-245, beta polypeptide (CYBB), mRNA.
  • 载体:现货载体
  • CDS区长度:1713
  • 翻译后氨基酸长度:570
  • 基因简介:Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole. [provided by RefSeq, Jul 2008]
  • 规格:10ul 质粒
CDS区参考序列: 点击查看序列
翻译后氨基酸参数序列: 点击查看序列