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- 商品货号：G113994
- accession：NM_001199138
- 基因别名：NLRC4
- 基因描述：Homo sapiens NLR family, CARD domain containing 4 (NLRC4), transcript variant 2, mRNA.
- 载体：现货载体
- CDS区长度：3075
- 翻译后氨基酸长度：1024
- TranscriptVariant：This variant (2) has an alternate 5' UTR exon and encodes the same protein, as compared to variant 1.
- 基因简介：In C. elegans, Ced4 binds and activates Ced3, an apoptotic initiator caspase, via caspase-associated recruitment domains (CARDs). Human Ced4 homologs include APAF1 (MIM 602233), NOD1/CARD4 (MIM 605980), and NOD2/CARD15 (MIM 605956). These proteins have at least 1 N-terminal CARD domain followed by a centrally located nucleotide-binding domain (NBD or NACHT) and a C-terminal regulatory domain, found only in mammals, that contains either WD40 repeats or leucine-rich repeats (LRRs). CARD12 is a member of the Ced4 family and can induce apoptosis.[supplied by OMIM, Mar 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
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