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人 PLCD1 (NM_006225) cDNA克隆
人 PLCD1 (NM_006225) cDNA克隆
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  • 商品货号:G117071
  • accession:NM_006225
  • 基因别名:PLCD1
  • 基因描述:Homo sapiens phospholipase C, delta 1 (PLCD1), transcript variant 2, mRNA.
  • 载体:现货载体
  • CDS区长度:2271
  • 翻译后氨基酸长度:756
  • TranscriptVariant:This variant (2) contains an alternate 5' terminal exon compared to transcript variant 1, and initiates translation from an in-frame upstream AUG, resulting in a shorter isoform (2) with a different N-terminus compared to isoform 1.
  • 基因简介:This gene encodes a member of the phospholipase C family. Phospholipase C isozymes play critical roles in intracellular signal transduction by catalyzing the hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers diacylglycerol (DAG) and inositol triphosphate (IP3). The encoded protein functions as a tumor suppressor in several types of cancer, and mutations in this gene are a cause of hereditary leukonychia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
  • 规格:10ul 质粒
CDS区参考序列: 点击查看序列
翻译后氨基酸参数序列: 点击查看序列