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- 商品货号：G117809
- accession：NM_139314
- 基因别名：ANGPTL4
- 基因描述：Homo sapiens angiopoietin-like 4 (ANGPTL4), transcript variant 1, mRNA.
- 载体：现货载体
- CDS区长度：1221
- 翻译后氨基酸长度：406
- TranscriptVariant：This variant (1) represents the longer transcript and encodes the longer isoform (a).
- 基因简介：This gene encodes a glycosylated, secreted protein containing a C-terminal fibrinogen domain. The encoded protein is induced by peroxisome proliferation activators and functions as a serum hormone that regulates glucose homeostasis, lipid metabolism, and insulin sensitivity. This protein can also act as an apoptosis survival factor for vascular endothelial cells and can prevent metastasis by inhibiting vascular growth and tumor cell invasion. The C-terminal domain may be proteolytically-cleaved from the full-length secreted protein. Decreased expression of this gene has been associated with type 2 diabetes. Alternative splicing results in multiple transcript variants. This gene was previously referred to as ANGPTL2 but has been renamed ANGPTL4. [provided by RefSeq, Sep 2013]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
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