• 商品货号：G120476

• accession：NM_003183
• 基因别名：ADAM17
• 基因描述：Homo sapiens ADAM metallopeptidase domain 17 (ADAM17), mRNA.
• 载体：现货载体
• CDS区长度：2475
• 翻译后氨基酸长度：824
• 基因简介：This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway. [provided by RefSeq, Jul 2008]
• 规格：10ul 质粒

CDS区参考序列： 点击查看序列

ATGAGGCAGTCTCTCCTATTCCTGACCAGCGTGGTTCCTTTCGTGCTGGCGCCGCGACCTCCGGATGACC
CGGGCTTCGGCCCCCACCAGAGACTCGAGAAGCTTGATTCTTTGCTCTCAGACTACGATATTCTCTCTTT
ATCTAATATCCAGCAGCATTCGGTAAGAAAAAGAGATCTACAGACTTCAACACATGTAGAAACACTACTA
ACTTTTTCAGCTTTGAAAAGGCATTTTAAATTATACCTGACATCAAGTACTGAACGTTTTTCACAAAATT
TCAAGGTCGTGGTGGTGGATGGTAAAAACGAAAGCGAGTACACTGTAAAATGGCAGGACTTCTTCACTGG
ACACGTGGTTGGTGAGCCTGACTCTAGGGTTCTAGCCCACATAAGAGATGATGATGTTATAATCAGAATC
AACACAGATGGGGCCGAATATAACATAGAGCCACTTTGGAGATTTGTTAATGATACCAAAGACAAAAGAA
TGTTAGTTTATAAATCTGAAGATATCAAGAATGTTTCACGTTTGCAGTCTCCAAAAGTGTGTGGTTATTT
AAAAGTGGATAATGAAGAGTTGCTCCCAAAAGGGTTAGTAGACAGAGAACCACCTGAAGAGCTTGTTCAT
CGAGTGAAAAGAAGAGCTGACCCAGATCCCATGAAGAACACGTGTAAATTATTGGTGGTAGCAGATCATC
GCTTCTACAGATACATGGGCAGAGGGGAAGAGAGTACAACTACAAATTACTTAATAGAGCTAATTGACAG
AGTTGATGACATCTATCGGAACACTTCATGGGATAATGCAGGTTTTAAAGGCTATGGAATACAGATAGAG
CAGATTCGCATTCTCAAGTCTCCACAAGAGGTAAAACCTGGTGAAAAGCACTACAACATGGCAAAAAGTT
ACCCAAATGAAGAAAAGGATGCTTGGGATGTGAAGATGTTGCTAGAGCAATTTAGCTTTGATATAGCTGA
GGAAGCATCTAAAGTTTGCTTGGCACACCTTTTCACATACCAAGATTTTGATATGGGAACTCTTGGATTA
GCTTATGTTGGCTCTCCCAGAGCAAACAGCCATGGAGGTGTTTGTCCAAAGGCTTATTATAGCCCAGTTG
GGAAGAAAAATATCTATTTGAATAGTGGTTTGACGAGCACAAAGAATTATGGTAAAACCATCCTTACAAA
GGAAGCTGACCTGGTTACAACTCATGAATTGGGACATAATTTTGGAGCAGAACATGATCCGGATGGTCTA
GCAGAATGTGCCCCGAATGAGGACCAGGGAGGGAAATATGTCATGTATCCCATAGCTGTGAGTGGCGATC
ACGAGAACAATAAGATGTTTTCAAACTGCAGTAAACAATCAATCTATAAGACCATTGAAAGTAAGGCCCA
GGAGTGTTTTCAAGAACGCAGCAATAAAGTTTGTGGGAACTCGAGGGTGGATGAAGGAGAAGAGTGTGAT
CCTGGCATCATGTATCTGAACAACGACACCTGCTGCAACAGCGACTGCACGTTGAAGGAAGGTGTCCAGT
GCAGTGACAGGAACAGTCCTTGCTGTAAAAACTGTCAGTTTGAGACTGCCCAGAAGAAGTGCCAGGAGGC
GATTAATGCTACTTGCAAAGGCGTGTCCTACTGCACAGGTAATAGCAGTGAGTGCCCGCCTCCAGGAAAT
GCTGAAGATGACACTGTTTGCTTGGATCTTGGCAAGTGTAAGGATGGGAAATGCATCCCTTTCTGCGAGA
GGGAACAGCAGCTGGAGTCCTGTGCATGTAATGAAACTGACAACTCCTGCAAGGTGTGCTGCAGGGACCT
TTCTGGCCGCTGTGTGCCCTATGTCGATGCTGAACAAAAGAACTTATTTTTGAGGAAAGGAAAGCCCTGT
ACAGTAGGATTTTGTGACATGAATGGCAAATGTGAGAAACGAGTACAGGATGTAATTGAACGATTTTGGG
ATTTCATTGACCAGCTGAGCATCAATACTTTTGGAAAGTTTTTAGCAGACAACATCGTTGGGTCTGTCCT
GGTTTTCTCCTTGATATTTTGGATTCCTTTCAGCATTCTTGTCCATTGTGTGGATAAGAAATTGGATAAA
CAGTATGAATCTCTGTCTCTGTTTCACCCCAGTAACGTCGAAATGCTGAGCAGCATGGATTCTGCATCGG
TTCGCATTATCAAACCCTTTCCTGCGCCCCAGACTCCAGGCCGCCTGCAGCCTGCCCCTGTGATCCCTTC
GGCGCCAGCAGCTCCAAAACTGGACCACCAGAGAATGGACACCATCCAGGAAGACCCCAGCACAGACTCA
CATATGGACGAGGATGGGTTTGAGAAGGACCCCTTCCCAAATAGCAGCACAGCTGCCAAGTCATTTGAGG
ATCTCACGGACCATCCGGTCACCAGAAGTGAAAAGGCTGCCTCCTTTAAACTGCAGCGTCAGAATCGTGT
TGACAGCAAAGAAACAGAGTGCTAA

翻译后氨基酸参数序列： 点击查看序列

ATGAGGCAGTCTCTCCTATTCCTGACCAGCGTGGTTCCTTTCGTGCTGGCGCCGCGACCTCCGGATGACC
CGGGCTTCGGCCCCCACCAGAGACTCGAGAAGCTTGATTCTTTGCTCTCAGACTACGATATTCTCTCTTT
ATCTAATATCCAGCAGCATTCGGTAAGAAAAAGAGATCTACAGACTTCAACACATGTAGAAACACTACTA
ACTTTTTCAGCTTTGAAAAGGCATTTTAAATTATACCTGACATCAAGTACTGAACGTTTTTCACAAAATT
TCAAGGTCGTGGTGGTGGATGGTAAAAACGAAAGCGAGTACACTGTAAAATGGCAGGACTTCTTCACTGG
ACACGTGGTTGGTGAGCCTGACTCTAGGGTTCTAGCCCACATAAGAGATGATGATGTTATAATCAGAATC
AACACAGATGGGGCCGAATATAACATAGAGCCACTTTGGAGATTTGTTAATGATACCAAAGACAAAAGAA
TGTTAGTTTATAAATCTGAAGATATCAAGAATGTTTCACGTTTGCAGTCTCCAAAAGTGTGTGGTTATTT
AAAAGTGGATAATGAAGAGTTGCTCCCAAAAGGGTTAGTAGACAGAGAACCACCTGAAGAGCTTGTTCAT
CGAGTGAAAAGAAGAGCTGACCCAGATCCCATGAAGAACACGTGTAAATTATTGGTGGTAGCAGATCATC
GCTTCTACAGATACATGGGCAGAGGGGAAGAGAGTACAACTACAAATTACTTAATAGAGCTAATTGACAG
AGTTGATGACATCTATCGGAACACTTCATGGGATAATGCAGGTTTTAAAGGCTATGGAATACAGATAGAG
CAGATTCGCATTCTCAAGTCTCCACAAGAGGTAAAACCTGGTGAAAAGCACTACAACATGGCAAAAAGTT
ACCCAAATGAAGAAAAGGATGCTTGGGATGTGAAGATGTTGCTAGAGCAATTTAGCTTTGATATAGCTGA
GGAAGCATCTAAAGTTTGCTTGGCACACCTTTTCACATACCAAGATTTTGATATGGGAACTCTTGGATTA
GCTTATGTTGGCTCTCCCAGAGCAAACAGCCATGGAGGTGTTTGTCCAAAGGCTTATTATAGCCCAGTTG
GGAAGAAAAATATCTATTTGAATAGTGGTTTGACGAGCACAAAGAATTATGGTAAAACCATCCTTACAAA
GGAAGCTGACCTGGTTACAACTCATGAATTGGGACATAATTTTGGAGCAGAACATGATCCGGATGGTCTA
GCAGAATGTGCCCCGAATGAGGACCAGGGAGGGAAATATGTCATGTATCCCATAGCTGTGAGTGGCGATC
ACGAGAACAATAAGATGTTTTCAAACTGCAGTAAACAATCAATCTATAAGACCATTGAAAGTAAGGCCCA
GGAGTGTTTTCAAGAACGCAGCAATAAAGTTTGTGGGAACTCGAGGGTGGATGAAGGAGAAGAGTGTGAT
CCTGGCATCATGTATCTGAACAACGACACCTGCTGCAACAGCGACTGCACGTTGAAGGAAGGTGTCCAGT
GCAGTGACAGGAACAGTCCTTGCTGTAAAAACTGTCAGTTTGAGACTGCCCAGAAGAAGTGCCAGGAGGC
GATTAATGCTACTTGCAAAGGCGTGTCCTACTGCACAGGTAATAGCAGTGAGTGCCCGCCTCCAGGAAAT
GCTGAAGATGACACTGTTTGCTTGGATCTTGGCAAGTGTAAGGATGGGAAATGCATCCCTTTCTGCGAGA
GGGAACAGCAGCTGGAGTCCTGTGCATGTAATGAAACTGACAACTCCTGCAAGGTGTGCTGCAGGGACCT
TTCTGGCCGCTGTGTGCCCTATGTCGATGCTGAACAAAAGAACTTATTTTTGAGGAAAGGAAAGCCCTGT
ACAGTAGGATTTTGTGACATGAATGGCAAATGTGAGAAACGAGTACAGGATGTAATTGAACGATTTTGGG
ATTTCATTGACCAGCTGAGCATCAATACTTTTGGAAAGTTTTTAGCAGACAACATCGTTGGGTCTGTCCT
GGTTTTCTCCTTGATATTTTGGATTCCTTTCAGCATTCTTGTCCATTGTGTGGATAAGAAATTGGATAAA
CAGTATGAATCTCTGTCTCTGTTTCACCCCAGTAACGTCGAAATGCTGAGCAGCATGGATTCTGCATCGG
TTCGCATTATCAAACCCTTTCCTGCGCCCCAGACTCCAGGCCGCCTGCAGCCTGCCCCTGTGATCCCTTC
GGCGCCAGCAGCTCCAAAACTGGACCACCAGAGAATGGACACCATCCAGGAAGACCCCAGCACAGACTCA
CATATGGACGAGGATGGGTTTGAGAAGGACCCCTTCCCAAATAGCAGCACAGCTGCCAAGTCATTTGAGG
ATCTCACGGACCATCCGGTCACCAGAAGTGAAAAGGCTGCCTCCTTTAAACTGCAGCGTCAGAATCGTGT
TGACAGCAAAGAAACAGAGTGCTAA