• 商品货号：G125184

• accession：NM_004857
• 基因别名：AKAP5
• 基因描述：Homo sapiens A kinase (PRKA) anchor protein 5 (AKAP5), mRNA.
• 载体：现货载体
• CDS区长度：1284
• 翻译后氨基酸长度：427
• 基因简介：The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to the RII-beta regulatory subunit of PKA, and also to protein kinase C and the phosphatase calcineurin. It is predominantly expressed in cerebral cortex and may anchor the PKA protein at postsynaptic densities (PSD) and be involved in the regulation of postsynaptic events. It is also expressed in T lymphocytes and may function to inhibit interleukin-2 transcription by disrupting calcineurin-dependent dephosphorylation of NFAT. [provided by RefSeq, Jul 2008]
• 规格：10ul 质粒

CDS区参考序列： 点击查看序列

ATGGAAACCACAATTTCAGAAATTCATGTAGAAAACAAGGATGAGAAGAGATCAGCAGAAGGTAGTCCTG
GGGCTGAAAGGCAGAAGGAAAAGGCATCCATGCTTTGCTTCAAGAGAAGAAAGAAAGCAGCCAAAGCACT
GAAGCCCAAAGCTGGCTCTGAAGCTGCTGATGTGGCAAGGAAGTGTCCACAAGAAGCAGGAGCTTCTGAT
CAGCCAGAGCCCACACGGGGGGCCTGGGCCTCACTCAAACGTCTTGTAACACGCAGGAAAAGGTCAGAGT
CTTCAAAGCAGCAAAAGCCATTGGAGGGTGAAATGCAACCTGCAATAAATGCTGAGGATGCTGATCTTTC
TAAGAAAAAGGCAAAATCTAGACTTAAGATTCCCTGCATAAAATTCCCAAGAGGGCCAAAAAGGAGTAAT
CATTCCAAAATTATAGAAGACTCAGACTGCAGCATCAAAGTCCAGGAAGAAGCTGAAATTTTGGATATAC
AAACACAGACCCCATTGAATGATCAGGCAACAAAGGCTAAGTCAACCCAGGATCTAAGTGAAGGCATCTC
ACGGAAAGATGGTGATGAGGTCTGTGAATCAAATGTGAGCAATAGCACAACTTCTGGAGAGAAAGTGATT
TCAGTAGAACTTGGATTAGATAATGGGCATTCTGCTATTCAAACGGGAACTCTAATCCTTGAAGAAATTG
AAACGATCAAGGAAAAACAAGATGTTCAACCCCAGCAAGCAAGCCCACTTGAAACTTCAGAAACAGACCA
TCAGCAGCCAGTACTTTCTGATGTTCCTCCTTTACCTGCAATTCCAGATCAACAAATTGTGGAAGAAGCC
AGTAACAGTACCCTAGAAAGTGCACCAAATGGAAAAGACTATGAAAGTACAGAGATTGTAGCTGAAGAAA
CTAAGCCAAAAGATACTGAATTGAGCCAAGAATCAGATTTTAAAGAAAATGGGATCACTGAAGAGAAATC
CAAATCAGAAGAAAGCAAAAGAATGGAGCCAATTGCTATTATTATTACAGACACTGAAATCAGTGAATTT
GATGTTACAAAATCTAAAAATGTCCCTAAGCAATTCTTAATTTCAGCTGAAAATGAGCAAGTAGGGGTTT
TTGCTAATGATAATGGTTTTGAGGATAGAACTTCAGAACAATATGAAACACTCTTAATTGAAACAGCCTC
TTCTCTAGTCAAGAATGCTATTCAGTTGTCAATAGAACAGCTGGTTAATGAAATGGCCTCTGATGATAAT
AAAATAAACAATCTTCTACAGTGA

翻译后氨基酸参数序列： 点击查看序列

ATGGAAACCACAATTTCAGAAATTCATGTAGAAAACAAGGATGAGAAGAGATCAGCAGAAGGTAGTCCTG
GGGCTGAAAGGCAGAAGGAAAAGGCATCCATGCTTTGCTTCAAGAGAAGAAAGAAAGCAGCCAAAGCACT
GAAGCCCAAAGCTGGCTCTGAAGCTGCTGATGTGGCAAGGAAGTGTCCACAAGAAGCAGGAGCTTCTGAT
CAGCCAGAGCCCACACGGGGGGCCTGGGCCTCACTCAAACGTCTTGTAACACGCAGGAAAAGGTCAGAGT
CTTCAAAGCAGCAAAAGCCATTGGAGGGTGAAATGCAACCTGCAATAAATGCTGAGGATGCTGATCTTTC
TAAGAAAAAGGCAAAATCTAGACTTAAGATTCCCTGCATAAAATTCCCAAGAGGGCCAAAAAGGAGTAAT
CATTCCAAAATTATAGAAGACTCAGACTGCAGCATCAAAGTCCAGGAAGAAGCTGAAATTTTGGATATAC
AAACACAGACCCCATTGAATGATCAGGCAACAAAGGCTAAGTCAACCCAGGATCTAAGTGAAGGCATCTC
ACGGAAAGATGGTGATGAGGTCTGTGAATCAAATGTGAGCAATAGCACAACTTCTGGAGAGAAAGTGATT
TCAGTAGAACTTGGATTAGATAATGGGCATTCTGCTATTCAAACGGGAACTCTAATCCTTGAAGAAATTG
AAACGATCAAGGAAAAACAAGATGTTCAACCCCAGCAAGCAAGCCCACTTGAAACTTCAGAAACAGACCA
TCAGCAGCCAGTACTTTCTGATGTTCCTCCTTTACCTGCAATTCCAGATCAACAAATTGTGGAAGAAGCC
AGTAACAGTACCCTAGAAAGTGCACCAAATGGAAAAGACTATGAAAGTACAGAGATTGTAGCTGAAGAAA
CTAAGCCAAAAGATACTGAATTGAGCCAAGAATCAGATTTTAAAGAAAATGGGATCACTGAAGAGAAATC
CAAATCAGAAGAAAGCAAAAGAATGGAGCCAATTGCTATTATTATTACAGACACTGAAATCAGTGAATTT
GATGTTACAAAATCTAAAAATGTCCCTAAGCAATTCTTAATTTCAGCTGAAAATGAGCAAGTAGGGGTTT
TTGCTAATGATAATGGTTTTGAGGATAGAACTTCAGAACAATATGAAACACTCTTAATTGAAACAGCCTC
TTCTCTAGTCAAGAATGCTATTCAGTTGTCAATAGAACAGCTGGTTAATGAAATGGCCTCTGATGATAAT
AAAATAAACAATCTTCTACAGTGA