- 商品货号:F110429
- accession:NM_002023
- 基因别名:FMOD
- 基因描述:Homo sapiens fibromodulin (FMOD), transcript variant 1, mRNA.
- 载体: 现货载体
- CDS区长度:1131
- 翻译后氨基酸长度:376
- TranscriptVariant:This variant (1) represents the longer transcript and encodes the supported protein.
- 基因简介:Fibromodulin belongs to the family of small interstitial proteoglycans. The encoded protein possesses a central region containing leucine-rich repeats with 4 keratan sulfate chains, flanked by terminal domains containing disulphide bonds. Owing to the interaction with type I and type II collagen fibrils and in vitro inhibition of fibrillogenesis, the encoded protein may play a role in the assembly of extracellular matrix. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix. Sequence variations in this gene may be associated with the pathogenesis of high myopia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
- 载体信息:自有图片地址
- 规格:10ul 质粒
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