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人TDG(NM_003211)ORF克隆
人TDG(NM_003211)ORF克隆
会员等级价V
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  • 商品货号:F110753
  • accession:NM_003211
  • 基因别名:TDG
  • 基因描述:Homo sapiens thymine-DNA glycosylase (TDG), mRNA.
  • 载体: 现货载体
  • CDS区长度:1233
  • 翻译后氨基酸长度:410
  • 基因简介:The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12. [provided by RefSeq, Jul 2008]
  • 载体信息:自有图片地址
  • 规格:10ul 质粒
CDS区参考序列: 点击查看序列
翻译后氨基酸参数序列: 点击查看序列