• 商品货号：F112836

• accession：NM_001343
• 基因别名：DAB2
• 基因描述：Homo sapiens Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) (DAB2), transcript variant 1, mRNA.
• 载体： 现货载体
• CDS区长度：2313
• 翻译后氨基酸长度：770
• TranscriptVariant：This variant (1) represents the predominant transcript, and encodes the longer isoform (1).
• 基因简介：This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells, but is down-regulated or absent from ovarian carcinoma cell lines, suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2, an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras), via its C-terminal proline-rich sequences, and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
• 载体信息：自有图片地址
• 规格：10ul 质粒

CDS区参考序列： 点击查看序列

ATGTCTAACGAAGTAGAAACAAGTGCAACCAATGGTCAGCCCGACCAACAGGCCGCACCAAAAGCACCCTCAAAGAAGGAAAAAAAGAAAGGCCCTGAAAAGACAGATGAATATCTCTTAGCAAGGTTCAAAGGCGATGGTGTAAAATATAAGGCCAAGCTGATTGGCATTGATGATGTGCCAGATGCAAGAGGGGATAAAATGAGCCAAGACTCTATGATGAAACTAAAGGGAATGGCGGCAGCTGGTCGGTCTCAGGGACAACACAAACAAAGGATCTGGGTCAACATTTCCCTTTCTGGGATAAAAATAATTGATGAGAAAACTGGGGTAATAGAGCATGAACATCCAGTAAATAAGATTTCTTTCATTGCCCGTGATGTGACAGACAACCGGGCATTTGGTTACGTGTGTGGAGGAGAAGGCCAGCATCAGTTTTTTGCCATAAAAACCGGGCAACAGGCTGAACCATTAGTTGTTGATCTTAAAGACCTTTTTCAAGTTATCTATAATGTAAAGAAAAAGGAAGAAGAAAAGAAAAAGATAGAGGAAGCCAGCAAAGCAGTTGAGAATGGGAGTGAGGCCCTAATGATTCTAGATGACCAAACTAACAAACTGAAATCGGGTGTTGACCAGATGGATTTGTTTGGGGACATGTCTACACCTCCTGACCTAAATAGTCCAACAGAAAGCAAAGATATCCTGTTAGTGGATCTAAACTCTGAAATCGACACCAATCAGAATTCTTTAAGAGAAAATCCATTCTTAACAAACGGCATCACCTCCTGTTCTCTTCCTCGACCAACGCCTCAGGCATCCTTCTTGCCTGAAAATGCCTTTTCTGCCAATCTCAACTTCTTTCCCACCCCTAATCCTGATCCTTTCCGTGACGATCCTTTCACACAGCCAGACCAATCGACACCTTCTTCGTTTGATTCTCTCAAATCTCCAGATCAGAAGAAAGAGAATTCGAGTAGCTCGTCTACTCCGCTGAGTAATGGGCCCCTGAATGGTGATGTTGACTACTTTGGTCAGCAATTTGACCAGATCTCTAACCGGACTGGCAAACAGGAAGCTCAGGCAGGCCCATGGCCCTTTTCAAGTTCGCAAACCCAGCCAGCAGTGAGAACTCAAAATGGGGTATCTGAAAGAGAACAGAACGGCTTCTCTGTCAAATCCTCCCCGAACCCTTTTGTGGGAAGCCCTCCCAAAGGACTGTCCATACAGAATGGCGTAAAGCAGGACTTGGAAAGCTCTGTCCAGTCCTCACCACATGACTCCATAGCCATTATCCCACCTCCACAAAGTACCAAACCAGGAAGAGGCAGAAGGACTGCTAAGTCTTCAGCCAATGACTTGCTTGCATCAGACATCTTTGCTCCTCCCGTCTCAGAACCTTCAGGCCAGGCGTCACCCACAGGACAACCTACAGCCCTGCAGCCCAACCCTCTGGATCTCTTCAAAACAAGTGCTCCTGCCCCAGTGGGGCCCCTGGTGGGTCTAGGTGGTGTAACTGTCACACTCCCTCAGGCAGGACCATGGAACACAGCATCTTTGGTCTTCAATCAGTCCCCTTCAATGGCTCCGGGAGCCATGATGGGTGGTCAACCTTCAGGTTTTAGTCAGCCCGTCATTTTTGGTACAAGTCCAGCTGTTTCAGGTTGGAACCAGCCTTCACCCTTTGCAGCCTCAACTCCCCCTCCAGTGCCTGTTGTCTGGGGCCCTTCTGCATCTGTGGCACCCAATGCTTGGTCAACAACAAGCCCTTTGGGGAATCCTTTTCAGAGCAATATTTTTCCAGCTCCTGCTGTGTCCACTCAGCCCCCATCCATGCACTCCTCTCTCCTGGTCACTCCTCCTCAGCCACCTCCCAGAGCTGGCCCTCCCAAGGACATCTCCAGTGATGCCTTCACTGCCTTAGACCCACTTGGGGATAAAGAGATCAAGGATGTGAAAGAAATGTTTAAGGATTTCCAACTGCGGCAGCCACCTGCTGTGCCCGCGCGGAAGGGAGAGCAGACTTCTTCTGGGACTTTGAGTGCCTTTGCCAGTTATTTCAACAGCAAGGTTGGCATTCCTCAGGAGAATGCAGACCATGATGACTTTGATGCTAATCAACTATTGAACAAGATCAATGAACCACCAAAGCCAGCTCCCAGACAAGTTTCCCTGCCAGTTACCAAATCTACTGACAATGCATTTGAGAACCCTTTCTTTAAAGATTCTTTTGGTTCATCACAAGCCTCTGTGGCTTCTTCTCAACCTGTATCTTCTGAGATGTATAGGGATCCATTTGGAAATCCTTTTGCCTAA

翻译后氨基酸参数序列： 点击查看序列

ATGTCTAACGAAGTAGAAACAAGTGCAACCAATGGTCAGCCCGACCAACAGGCCGCACCAAAAGCACCCTCAAAGAAGGAAAAAAAGAAAGGCCCTGAAAAGACAGATGAATATCTCTTAGCAAGGTTCAAAGGCGATGGTGTAAAATATAAGGCCAAGCTGATTGGCATTGATGATGTGCCAGATGCAAGAGGGGATAAAATGAGCCAAGACTCTATGATGAAACTAAAGGGAATGGCGGCAGCTGGTCGGTCTCAGGGACAACACAAACAAAGGATCTGGGTCAACATTTCCCTTTCTGGGATAAAAATAATTGATGAGAAAACTGGGGTAATAGAGCATGAACATCCAGTAAATAAGATTTCTTTCATTGCCCGTGATGTGACAGACAACCGGGCATTTGGTTACGTGTGTGGAGGAGAAGGCCAGCATCAGTTTTTTGCCATAAAAACCGGGCAACAGGCTGAACCATTAGTTGTTGATCTTAAAGACCTTTTTCAAGTTATCTATAATGTAAAGAAAAAGGAAGAAGAAAAGAAAAAGATAGAGGAAGCCAGCAAAGCAGTTGAGAATGGGAGTGAGGCCCTAATGATTCTAGATGACCAAACTAACAAACTGAAATCGGGTGTTGACCAGATGGATTTGTTTGGGGACATGTCTACACCTCCTGACCTAAATAGTCCAACAGAAAGCAAAGATATCCTGTTAGTGGATCTAAACTCTGAAATCGACACCAATCAGAATTCTTTAAGAGAAAATCCATTCTTAACAAACGGCATCACCTCCTGTTCTCTTCCTCGACCAACGCCTCAGGCATCCTTCTTGCCTGAAAATGCCTTTTCTGCCAATCTCAACTTCTTTCCCACCCCTAATCCTGATCCTTTCCGTGACGATCCTTTCACACAGCCAGACCAATCGACACCTTCTTCGTTTGATTCTCTCAAATCTCCAGATCAGAAGAAAGAGAATTCGAGTAGCTCGTCTACTCCGCTGAGTAATGGGCCCCTGAATGGTGATGTTGACTACTTTGGTCAGCAATTTGACCAGATCTCTAACCGGACTGGCAAACAGGAAGCTCAGGCAGGCCCATGGCCCTTTTCAAGTTCGCAAACCCAGCCAGCAGTGAGAACTCAAAATGGGGTATCTGAAAGAGAACAGAACGGCTTCTCTGTCAAATCCTCCCCGAACCCTTTTGTGGGAAGCCCTCCCAAAGGACTGTCCATACAGAATGGCGTAAAGCAGGACTTGGAAAGCTCTGTCCAGTCCTCACCACATGACTCCATAGCCATTATCCCACCTCCACAAAGTACCAAACCAGGAAGAGGCAGAAGGACTGCTAAGTCTTCAGCCAATGACTTGCTTGCATCAGACATCTTTGCTCCTCCCGTCTCAGAACCTTCAGGCCAGGCGTCACCCACAGGACAACCTACAGCCCTGCAGCCCAACCCTCTGGATCTCTTCAAAACAAGTGCTCCTGCCCCAGTGGGGCCCCTGGTGGGTCTAGGTGGTGTAACTGTCACACTCCCTCAGGCAGGACCATGGAACACAGCATCTTTGGTCTTCAATCAGTCCCCTTCAATGGCTCCGGGAGCCATGATGGGTGGTCAACCTTCAGGTTTTAGTCAGCCCGTCATTTTTGGTACAAGTCCAGCTGTTTCAGGTTGGAACCAGCCTTCACCCTTTGCAGCCTCAACTCCCCCTCCAGTGCCTGTTGTCTGGGGCCCTTCTGCATCTGTGGCACCCAATGCTTGGTCAACAACAAGCCCTTTGGGGAATCCTTTTCAGAGCAATATTTTTCCAGCTCCTGCTGTGTCCACTCAGCCCCCATCCATGCACTCCTCTCTCCTGGTCACTCCTCCTCAGCCACCTCCCAGAGCTGGCCCTCCCAAGGACATCTCCAGTGATGCCTTCACTGCCTTAGACCCACTTGGGGATAAAGAGATCAAGGATGTGAAAGAAATGTTTAAGGATTTCCAACTGCGGCAGCCACCTGCTGTGCCCGCGCGGAAGGGAGAGCAGACTTCTTCTGGGACTTTGAGTGCCTTTGCCAGTTATTTCAACAGCAAGGTTGGCATTCCTCAGGAGAATGCAGACCATGATGACTTTGATGCTAATCAACTATTGAACAAGATCAATGAACCACCAAAGCCAGCTCCCAGACAAGTTTCCCTGCCAGTTACCAAATCTACTGACAATGCATTTGAGAACCCTTTCTTTAAAGATTCTTTTGGTTCATCACAAGCCTCTGTGGCTTCTTCTCAACCTGTATCTTCTGAGATGTATAGGGATCCATTTGGAAATCCTTTTGCCTAA