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- 商品货号：G151893
- accession：NM_001127671
- 基因别名：LIFR
- 基因描述：Homo sapiens leukemia inhibitory factor receptor alpha (LIFR), transcript variant 1, mRNA.
- 载体：现货载体
- CDS区长度：3294
- 翻译后氨基酸长度：1097
- TranscriptVariant：This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.
- 基因简介：This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5;8)(p13;q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
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